Mitochondrial dysfunction in type 2 diabetes mellitus - an organ-based analysis.pdf
journal contributionposted on 05.03.2019, 21:36 by Mark Pinti, Garrett Fink, Quincy A. Hathaway, Andrya J. Durr, Amina Kunovac, John M. Hollander
The goal of this review is to highlight mitochondrial
dysfunction observed throughout major organ systems in the context of T2DM and to present new ideas for future research directions based on novel experimental and technological innovations in mitochondrial biology. Finally, the field of mitochondria- targeted therapeutics is discussed, with an emphasis on novel therapeutic strategies to restore mitochondrial homeostasis in the setting of T2DM.