Quincy A Hathaway - Genomics Highlight EB 2018 - Talk_FINAL_jh.pptx (8.91 MB)
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posted on 2019-03-05, 21:36 authored by Quincy A. HathawayOur results suggest that
during type 2 diabetes mellitus, nuclear-encoded proteins that comprise the
mitochondrial proteome and are involved in protein and RNA import can be
epigenetically altered. Mitochondrial subpopulations also differentially
express RNA during diabetic insult, with the SSM being more detrimentally
impacted. Epigenetic alterations, and changes in RNA, reveal how environmental
changes to the nuclear genome could shape mitochondrial structure and function.