Mwiza et al bloodbld2022015787 (3).pdf (1.54 MB)
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posted on 2023-01-23, 20:42 authored by Robert
H. Lee, David S. Paul, Lori A. Hole, Brian Cooley, Bernhard Nieswandt, Wyatt J. Schug, Tomohiro Kawano, Nigel Mackman, Alisa S. Wolberg, Wolfgang Bergmeier, Jean-Marie MwizaPlatelet activation via
GPCRs and ITAM
receptors is critical for
platelet–neutrophil
aggregate formation
during VT initiation
in mice.
Inhibitors of these
pathways, especially
of ITAM receptor
signaling, may provide
a unique strategy to
more safely prevent VT.
