Zhang et al, final, PMID29330215 .full.pdf (1.53 MB)
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Zhang et al, final, PMID29330215 .full.pdf

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posted on 2019-03-07, 17:24 authored by Xiaokan Zhang, Ruiping Ji, xianghai liao, Estibaliz Castillero, Peter J. Kennel, danielle brunjes, Marcus Franz, Sven Mobius-Winkler, Konstantinos Drosatos, Isaac George, Emily Chen, Paolo Colombo, P. Christian Schulze
Our data suggest that increased levels of miR-195 in failing myocardium regulate a novel pathway that involves direct SIRT3 suppression and enzymatic inhibition via increased acetylation of PDH and ATP synthase that are essential for cardiac energy metabolism


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